Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791171 | 0.84 | RAB9A (0.44) | KDM4EMAPTALDH1A1RECQLGAA | |
| SCHEMBL3219704 | 0.74 | KCNH2 (0.42) | KDM4EMAPTALDH1A1RECQLHSD17B10 | |
| SCHEMBL1073716 | 0.73 | KARS1 (0.49) | CA12CA3CA4CA6CA5A | |
| SCHEMBL4669978 | 0.73 | MAPT (0.46) | KDM4EMAPTKAT2BHTR6GAA | |
| SCHEMBL5275210 | 0.72 | KMT2A (0.40) | MAPTCA12ALDH1A1TSHRLMNA | |
| SCHEMBL3294386 | 0.72 | TSHR (0.46) | KDM4EMAPTALDH1A1TSHRRECQL | |
| SCHEMBL16790977 | 0.72 | HRH3 (0.43) | KDM4EMAPTCA12CA3CA4 | |
| SCHEMBL31511712 | 0.71 | NAMPT (0.41) | PIM1PIM2PIM3HRH3 | |
| SCHEMBL1631571 | 0.70 | NPSR1 (0.50) | KDM4EALDH1A1HSD17B10LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL16766687 | 0.70 | ALDH1A1 (0.44) | KDM4EMAPTCA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018321-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |