Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695345 | 0.81 | KDM4E (0.55) | HPGDHSD17B10FFAR4TSHRALDH1A1 | |
| SCHEMBL7702356 | 0.78 | MAPT (0.46) | HPGDKMT2AHSD17B10MEN1HIF1A | |
| SCHEMBL7697660 | 0.75 | TSHR (0.48) | HPGDKMT2AHSD17B10TSHRALDH1A1 | |
| SCHEMBL8160152 | 0.74 | HPGD (0.44) | HPGDKMT2AHSD17B10GAAMEN1 | |
| SCHEMBL6946231 | 0.73 | POLB (0.46) | HPGDKMT2AHSD17B10GAAMEN1 | |
| SCHEMBL4613990 | 0.72 | LMNA (0.51) | KMT2AMEN1HIF1ATSHRALDH1A1 | |
| SCHEMBL2059516 | 0.72 | KMT2A (0.55) | HPGDKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL17980842 | 0.72 | TSHR (0.53) | KMT2AMEN1TSHRALDH1A1MAPK1 | |
| SCHEMBL27051702 | 0.70 | KMT2A (0.41) | HPGDKMT2AHSD17B10FFAR4ALDH1A1 | |
| SCHEMBL5512465 | 0.70 | ALDH1A1 (0.69) | HPGDKMT2AHSD17B10MEN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |