Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696391 | 0.91 | MAPT (0.54) | USP2KMT2AL3MBTL1MAPTTSHR | |
| SCHEMBL7697612 | 0.91 | L3MBTL1 (0.60) | KMT2AL3MBTL1MAPTSMN1; SMN2TP53 | |
| SCHEMBL7695332 | 0.90 | NPC1 (0.56) | USP2KMT2AL3MBTL1MAPTTSHR | |
| SCHEMBL7700066 | 0.88 | NPC1 (0.58) | KMT2AMAPTTSHRSMN1; SMN2TP53 | |
| SCHEMBL7703296 | 0.86 | DGAT1 (0.51) | USP2L3MBTL1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL7699160 | 0.85 | SMN1; SMN2 (0.57) | USP2KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL7698228 | 0.85 | MAPT (0.56) | L3MBTL1MAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL7699504 | 0.85 | MAPT (0.55) | KMT2AL3MBTL1MAPTSMN1; SMN2TP53 | |
| SCHEMBL7695065 | 0.84 | NPC1 (0.55) | KMT2AL3MBTL1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL7697604 | 0.83 | KDM4E (0.55) | KMT2AL3MBTL1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |