Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539792 | 0.81 | TSHR (0.50) | TSHRESR1LMNACYP1A2CYP2C19 | |
| SCHEMBL2830666 | 0.79 | HDAC3 (0.45) | TSHRESR1LMNACYP1A2CYP2C19 | |
| SCHEMBL25013199 | 0.76 | ALDH1A1 (0.67) | TSHRLMNACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8029452 | 0.76 | PKM (0.49) | LMNAMAPK1L3MBTL1TDP1RAB9A | |
| SCHEMBL3652003 | 0.75 | TSHR (0.53) | TSHRLMNASMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL16195344 | 0.72 | CYP3A4 (0.57) | TSHRCYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL10022750 | 0.72 | KDM4E (0.49) | TSHRESR1LMNACYP1A2CYP2C19 | |
| SCHEMBL18753071 | 0.71 | ALDH1A1 (0.40) | TSHRESR1LMNACYP1A2CYP2C19 | |
| SCHEMBL17470884 | 0.71 | ALDH1A1 (0.49) | TSHRLMNAMAPK1CYP3A4HPGD | |
| SCHEMBL23663766 | 0.71 | CYP1A2 (0.70) | TSHRESR1LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |