Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALPG | P10696 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783569 | 0.82 | HTT (0.44) | HTTALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL848935 | 0.82 | ALOX5 (0.38) | HTTKDM4ELMNAGAAALPG | |
| SCHEMBL24181276 | 0.77 | ALOX5 (0.35) | HTTMAPTTDP1POLBLMNA | |
| SCHEMBL2708355 | 0.77 | ALOX5 (0.35) | HTTMAPTTDP1POLBLMNA | |
| SCHEMBL10638306 | 0.76 | MAPT (0.47) | ALDH1A1MAPTTDP1KDM4EGAA | |
| SCHEMBL9273413 | 0.71 | LMNA (0.32) | HTTLMNAALOX5 | |
| SCHEMBL6442271 | 0.71 | LMNA (0.32) | HTTLMNAALOX5 | |
| SCHEMBL8388899 | 0.71 | POLB (0.38) | HTTALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL4945878 | 0.71 | LMNA (0.32) | HTTLMNAALOX5 | |
| SCHEMBL10602956 | 0.71 | HTT (0.39) | HTTALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012236-A1 | SUBSTITUTED TRIAZOLOPYRID(AZ)INES AS PLANT TREATMENT AGENTS (HERBICIDES) | BAYER CROPSCIENCE AG (DE) | 2002-02-14 | — | — | WO | disclosed |
| EP-0173153-B1 | BENZOCONDENSED HETEROCYCLIC COMPOUNDS CONTAINING FLUOR, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |
| US-4757086-A | Insecticides, acaricides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4681955-A | INSECTICIDES, MITICIDES, PYROCATECHOLS, CARBONYL COMPOUNDS, CYCLIZATION, HALOGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |
| EP-0173152-A2 | Benzoyl ureas | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173153-A2 | Benzocondensed heterocyclic compounds containing fluor, process for their preparation and their use | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |