Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442271 | 0.82 | LMNA (0.32) | ALOX5LMNAHTTAHR | |
| SCHEMBL7696149 | 0.82 | HTT (0.39) | ALOX5LMNAHTTALPGKDM4E | |
| SCHEMBL4945878 | 0.82 | LMNA (0.32) | ALOX5KIF11LMNAHTTMAOA | |
| SCHEMBL9273413 | 0.82 | LMNA (0.32) | ALOX5LMNAHTTAHR | |
| SCHEMBL200514 | 0.81 | GPR3 (0.45) | ALOX5ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL7279047 | 0.78 | CTNNB1 (0.30) | CTNNB1WNT3A | |
| SCHEMBL24181276 | 0.77 | ALOX5 (0.35) | ALOX5ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL19492665 | 0.77 | ALOX5 (0.35) | ALOX5ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL8764608 | 0.77 | ALOX5 (0.35) | ALOX5ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL2708355 | 0.77 | ALOX5 (0.35) | ALOX5ABCG2ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | claimed |
| EP-3936192-B1 | PYRROLOPYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2025-04-09 | — | — | EP | claimed |
| EP-0893444-B1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | claimed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | claimed |
| EP-0893444-A1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | BAYER AG (DE) | 1999-01-27 | — | — | EP | claimed |
| JP-6329574-A | — | — | None | — | — | JP | disclosed |
| JP-11106383-A | — | — | None | — | — | JP | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230053726-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | VICKERS-SPLICE CO-INVESTMENT LLC (KY) | 2023-02-23 | — | — | US | disclosed |
| EP-0893444-A1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | BAYER AG (DE) | 1999-01-27 | — | — | EP | disclosed |
| EP-0623609-B1 | Process for the preparation of perfluoroalkoxy or perfluoroalkylthiobenzenes | BAYER AG (DE) | 1998-09-16 | — | — | EP | disclosed |
| US-5633218-A | CONTROLLING WEEDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| WO-1996022280-A1 | N-SUBSTITUTED 1-ACYLAMINOALKYL PIPERIDINES FOR TREATMENT OF CEREBRAL DISORDERS AND DEPRESSIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-25 | — | — | WO | disclosed |
| US-5463088-A | Process for preparing perfluoroalkoxy (alkylthio) benzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| JP-H06329574-A | PREPARATION OF PERFLUOROALKOXY(ALKYLTHIO) BENZENES | BAYER AG | 1994-11-29 | — | — | JP | disclosed |
| EP-0623609-A1 | Process for the preparation of perfluoroalkoxy or perfluoroalkylthiobenzenes | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |
| US-5283378-A | Process for the dechlorination and/or debromination of fluorine-and chlorine- and/or bromine-containing aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | DGKG, DGKA, DNER | ALOX5 688/4885ABCG2 2201/4885ITGB2 3502/4885 |
| US-20230053726-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | GSK3A, GSK3B, WNT1 | ALOX5 3170/4885ABCG2 4773/4885ITGB2 637/4885 |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | ALOX5 3118/4885ABCG2 4763/4885ITGB2 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.