Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701500 | 0.93 | GPBAR1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7698850 | 0.91 | GPBAR1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7701025 | 0.90 | IKBKB (0.45) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7699801 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7698844 | 0.85 | KDM4E (0.57) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7699568 | 0.84 | GPBAR1 (0.44) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL7693804 | 0.84 | IKBKB (0.45) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7697807 | 0.83 | GPBAR1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7695324 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7703225 | 0.81 | IKBKB (0.46) | ALDH1A1KDM4EHPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |