Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703305 | 0.91 | GPBAR1 (0.53) | IKBKBDGAT1GPBAR1MAPTKDM4E | |
| SCHEMBL7696153 | 0.90 | ALDH1A1 (0.47) | IKBKBDGAT1HDAC4HDAC8HDAC6 | |
| SCHEMBL7695161 | 0.89 | IKBKB (0.50) | IKBKBDGAT1HDAC4HDAC8HDAC6 | |
| SCHEMBL7701500 | 0.84 | GPBAR1 (0.47) | IKBKBDGAT1GPBAR1MAPTRXFP1 | |
| SCHEMBL7698850 | 0.81 | GPBAR1 (0.39) | DGAT1HDAC4HDAC8HDAC6GPBAR1 | |
| SCHEMBL7693804 | 0.81 | IKBKB (0.45) | IKBKBDGAT1HDAC4HDAC8HDAC6 | |
| SCHEMBL7699353 | 0.81 | HDAC4 (0.50) | IKBKBDGAT1HDAC4HDAC6KDM1A | |
| SCHEMBL7703225 | 0.81 | IKBKB (0.46) | IKBKBGPBAR1MAPTRXFP1KDM4E | |
| SCHEMBL7699801 | 0.80 | ALDH1A1 (0.51) | IKBKBMAPTRXFP1KDM4EALDH1A1 | |
| SCHEMBL7693955 | 0.79 | KDM4E (0.52) | IKBKBMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |