Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703305 | 0.91 | GPBAR1 (0.53) | IKBKBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7705474 | 0.90 | IKBKB (0.42) | IKBKBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7701500 | 0.88 | GPBAR1 (0.47) | IKBKBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7693990 | 0.85 | IKBKB (0.53) | IKBKBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7701275 | 0.82 | IKBKB (0.63) | IKBKBALDH1A1KDM4EMAPTNR1H4 | |
| SCHEMBL7693804 | 0.81 | IKBKB (0.45) | IKBKBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7701025 | 0.81 | IKBKB (0.45) | IKBKBALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7696153 | 0.81 | ALDH1A1 (0.47) | IKBKBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7699568 | 0.80 | GPBAR1 (0.44) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL7697807 | 0.79 | GPBAR1 (0.47) | IKBKBALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |