Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490455 | 0.77 | GAA (0.49) | APPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL9172620 | 0.77 | KMT2A (0.49) | APPGAAKMT2APOLBMAPT | |
| SCHEMBL9857796 | 0.76 | APP (0.55) | APPMEN1KMT2APOLBMAPT | |
| SCHEMBL490553 | 0.75 | CYP4F2 (0.55) | APPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL9487932 | 0.75 | APP (0.52) | APPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL7116001 | 0.74 | APP (0.58) | APPHSP90AA1HSP90AB1GAAIAPP | |
| SCHEMBL29160643 | 0.74 | NR1H4 (0.51) | APPGAAKMT2APOLBMAPT | |
| SCHEMBL30077234 | 0.74 | APP (0.58) | APPHSP90AA1HSP90AB1GAAIAPP | |
| SCHEMBL2131066 | 0.74 | APP (0.51) | APPHSP90AA1HSP90AB1GAAKMT2A | |
| SCHEMBL28861006 | 0.73 | ALDH1A1 (0.42) | HSP90AA1HSP90AB1GAAMAPTTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079173-A1 | BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | claimed |