Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700433 | 0.79 | KMT2A (0.69) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7700431 | 0.78 | TP53 (0.47) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7696411 | 0.77 | MEN1 (0.44) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7701852 | 0.76 | MAPT (0.51) | KMT2AMEN1TP53ALDH1A1HPGD | |
| SCHEMBL7700535 | 0.75 | KMT2A (0.52) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7698779 | 0.74 | MAPT (0.56) | KMT2AMEN1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL7701850 | 0.74 | TP53 (0.40) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7696705 | 0.74 | TSHR (0.47) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7703760 | 0.74 | TSHR (0.40) | KMT2AMEN1TP53SMN1; SMN2TSHR | |
| SCHEMBL7698777 | 0.72 | MAPT (0.40) | KMT2AMEN1TP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |