Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700431 | 0.74 | TP53 (0.47) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7696409 | 0.74 | KMT2A (0.43) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7701850 | 0.73 | TP53 (0.40) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7696411 | 0.72 | MEN1 (0.44) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7698777 | 0.72 | MAPT (0.40) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7700433 | 0.71 | KMT2A (0.69) | TSHRALDH1A1MAPTTP53THRB | |
| SCHEMBL7699872 | 0.70 | ALDH1A1 (0.42) | TSHRALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7701852 | 0.69 | MAPT (0.51) | ALDH1A1MAPTTP53KMT2AMEN1 | |
| SCHEMBL7700867 | 0.68 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7700535 | 0.67 | KMT2A (0.52) | TSHRALDH1A1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |