Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700202 | 0.92 | EPHX2 (0.52) | EPHX2DGAT1TP53MEN1RAB9A | |
| SCHEMBL7693770 | 0.91 | TSHR (0.50) | MAPTEPHX2TP53THRBSTAT3 | |
| SCHEMBL7701384 | 0.90 | EPHX2 (0.51) | MAPTEPHX2DGAT1TP53POLB | |
| SCHEMBL7701962 | 0.89 | TAOK1 (0.54) | MAPTEPHX2DGAT1TP53POLB | |
| SCHEMBL7699756 | 0.88 | EPHX2 (0.48) | MAPTEPHX2DGAT1STAT3POLB | |
| SCHEMBL7698148 | 0.87 | PTGES (0.49) | MAPTDGAT1TP53THRBLMNA | |
| SCHEMBL7693795 | 0.86 | KDM4E (0.51) | EPHX2DGAT1TP53POLBMEN1 | |
| SCHEMBL7701450 | 0.85 | EPHX2 (0.48) | MAPTEPHX2DGAT1TP53POLB | |
| SCHEMBL7693811 | 0.85 | NPC1 (0.50) | EPHX2DGAT1TP53POLBMEN1 | |
| SCHEMBL7700054 | 0.85 | NPC1 (0.50) | MAPTEPHX2DGAT1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |