Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699225 | 0.89 | PTGES (0.53) | PTGESCNR1CNR2DGAT1SMO | |
| SCHEMBL7696332 | 0.88 | PTGES (0.49) | PTGESMAPTKDM4EHPGDNPC1 | |
| SCHEMBL7696456 | 0.87 | MAPT (0.51) | MAPTRAB9ATHRBTP53LMNA | |
| SCHEMBL7700202 | 0.86 | EPHX2 (0.52) | PTGESNPC1RAB9AHSD17B10TP53 | |
| SCHEMBL7693795 | 0.86 | KDM4E (0.51) | PTGESKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7693770 | 0.85 | TSHR (0.50) | MAPTKDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL7701384 | 0.85 | EPHX2 (0.51) | PTGESMAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL7693811 | 0.85 | NPC1 (0.50) | PTGESKDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL7700947 | 0.85 | KDM4E (0.47) | PTGESKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7700054 | 0.85 | NPC1 (0.50) | PTGESMAPTKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |