Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691825 | 0.91 | JAK2 (0.46) | MAPK14NTRK1JAK2MAPK13GAA | |
| SCHEMBL7700675 | 0.88 | MAPK14 (0.43) | MAPK14NTRK1JAK2MAPK13MAPK12 | |
| SCHEMBL7693923 | 0.88 | MAPK14 (0.45) | MAPK14NTRK1JAK2MAPK13MAPK12 | |
| SCHEMBL7697558 | 0.85 | MAPK14 (0.47) | MAPK14NTRK1JAK2MAPK13GAA | |
| SCHEMBL7697861 | 0.84 | MAPK14 (0.47) | MAPK14NTRK1JAK2MAPK13MAPK12 | |
| SCHEMBL7696568 | 0.84 | MAPK14 (0.41) | MAPK14NTRK1MAPK13MAPK12MAPK11 | |
| SCHEMBL7690441 | 0.83 | MAPK14 (0.47) | MAPK14NTRK1MAPK13MAPK12MAPK11 | |
| SCHEMBL7691122 | 0.82 | MAPK14 (0.50) | MAPK14JAK2MAPK13GAAMAPK12 | |
| SCHEMBL7695893 | 0.82 | SOD1 (0.46) | MAPK14 | |
| SCHEMBL7694572 | 0.82 | MAPT (0.39) | MAPK14NTRK1JAK2MAPK13GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |