Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691048 | 0.91 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL7700675 | 0.85 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7694525 | 0.84 | MAPK14 (0.39) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7693923 | 0.83 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7697564 | 0.83 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7696568 | 0.81 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7691122 | 0.81 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7695893 | 0.81 | SOD1 (0.46) | MAPK14SMN1; SMN2 | |
| SCHEMBL7697861 | 0.80 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11TRPV1 | |
| SCHEMBL7696758 | 0.78 | TP53 (0.40) | MAPK14NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |