Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697247 | 0.92 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7700675 | 0.91 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7697861 | 0.84 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7697564 | 0.84 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7693923 | 0.84 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7694572 | 0.83 | MAPT (0.39) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7691136 | 0.82 | BRAF (0.46) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7690441 | 0.81 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7693916 | 0.81 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7697558 | 0.79 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |