Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700675 | 0.85 | MAPK14 (0.43) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL7696568 | 0.83 | MAPK14 (0.41) | MAPTALDH1A1KDM4EHPGDMAPK14 | |
| SCHEMBL7697861 | 0.82 | MAPK14 (0.47) | MAPTTRPV1MAPK14MAPK13NTRK1 | |
| SCHEMBL7693923 | 0.82 | MAPK14 (0.45) | MAPK14MAPK13NTRK1JAK2MAPK12 | |
| SCHEMBL7697564 | 0.82 | MAPK14 (0.41) | MAPK14MAPK13NTRK1GAAJAK2 | |
| SCHEMBL7690441 | 0.78 | MAPK14 (0.47) | SMN1; SMN2TRPV1MAPK14MAPK13NTRK1 | |
| SCHEMBL7691122 | 0.77 | MAPK14 (0.50) | MAPTSMN1; SMN2LMNAHTTMAPK14 | |
| SCHEMBL7695893 | 0.77 | SOD1 (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL7691048 | 0.76 | MAPK14 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL7694525 | 0.76 | MAPK14 (0.39) | RAB9ANPC1TRPV1MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |