Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.57 |
| ▸ | EDNRB | P24530 | 6/20 | 0.57 |
| ▸ | DHPS | P49366 | 12/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696683 | 0.92 | EDNRA (0.56) | EDNRAEDNRBDHPS | |
| SCHEMBL7699797 | 0.90 | DHPS (0.56) | EDNRAEDNRBDHPS | |
| SCHEMBL7850706 | 0.86 | EDNRA (0.52) | EDNRAEDNRBDHPS | |
| SCHEMBL7699796 | 0.82 | EDNRA (0.52) | EDNRAEDNRBDHPS | |
| SCHEMBL4061147 | 0.79 | DHPS (0.80) | EDNRAEDNRBDHPS | |
| SCHEMBL7850330 | 0.79 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7848794 | 0.79 | EDNRA (0.65) | EDNRAEDNRBDHPS | |
| SCHEMBL7700301 | 0.78 | DHPS (0.64) | EDNRAEDNRBDHPS | |
| SCHEMBL4060092 | 0.77 | EDNRB (0.67) | EDNRAEDNRBDHPS | |
| SCHEMBL7209693 | 0.75 | DHPS (0.58) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |