Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698882 | 0.95 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7702793 | 0.95 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7698851 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7700535 | 0.87 | KMT2A (0.52) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7701081 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7704682 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7667933 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7700470 | 0.83 | KMT2A (0.44) | ALDH1A1KDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL7699967 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTTMAPTL3MBTL1 | |
| SCHEMBL7695104 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |