Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701081 | 0.99 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7698851 | 0.95 | ALDH1A1 (0.60) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7698882 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTMAPTGAA | |
| SCHEMBL7702793 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7696797 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL7695231 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7698848 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7697447 | 0.78 | ALDH1A1 (0.82) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7700628 | 0.76 | MAPT (0.76) | ALDH1A1KDM4EHTTPOLBMAPT | |
| SCHEMBL7700535 | 0.75 | KMT2A (0.52) | ALDH1A1KDM4EHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |