Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701108 | 0.84 | KMT2A (0.62) | KMT2ATSHRMEN1CYP2C19GAA | |
| SCHEMBL7696797 | 0.83 | ALDH1A1 (0.50) | KMT2ATSHRMEN1GAAL3MBTL1 | |
| SCHEMBL7700596 | 0.81 | L3MBTL1 (0.53) | KMT2AMEN1GAAL3MBTL1LMNA | |
| SCHEMBL7699708 | 0.80 | L3MBTL1 (0.56) | KMT2AMEN1GAAL3MBTL1LMNA | |
| SCHEMBL7698882 | 0.79 | ALDH1A1 (0.48) | KMT2ATSHRMEN1HSD17B10GAA | |
| SCHEMBL7702793 | 0.79 | ALDH1A1 (0.48) | KMT2ATSHRMEN1GAAL3MBTL1 | |
| SCHEMBL7700535 | 0.78 | KMT2A (0.52) | KMT2ATSHRMEN1HSD17B10GAA | |
| SCHEMBL7698770 | 0.77 | MAPT (0.61) | KMT2ATSHRMEN1GAAALDH1A1 | |
| SCHEMBL7699365 | 0.76 | L3MBTL1 (0.75) | KMT2ATSHRMEN1HSD17B10GAA | |
| SCHEMBL15307437 | 0.76 | ALDH1A1 (0.66) | KMT2ATSHRMEN1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |