Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697861 | 0.91 | MAPK14 (0.47) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7691825 | 0.83 | JAK2 (0.46) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7700746 | 0.83 | JAK2 (0.48) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7697247 | 0.83 | MAPK14 (0.48) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7700675 | 0.78 | MAPK14 (0.43) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7691063 | 0.77 | SOD1 (0.50) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7693916 | 0.77 | MAPK14 (0.51) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7695414 | 0.76 | MAPK13 (0.42) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7697558 | 0.75 | MAPK14 (0.47) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7692071 | 0.75 | MAPK14 (0.49) | JAK2MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |