Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 4/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693916 | 0.94 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7700746 | 0.92 | JAK2 (0.48) | MAPK14MAPK13MAPK12MAPK11CDK8 | |
| SCHEMBL7697558 | 0.87 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7697247 | 0.85 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7692769 | 0.85 | KDM4E (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7693923 | 0.85 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7696568 | 0.79 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7691825 | 0.78 | JAK2 (0.46) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL7691063 | 0.76 | SOD1 (0.50) | MAPK14MAPK13MAPK12MAPK11GSK3A | |
| SCHEMBL7696799 | 0.75 | JAK2 (0.45) | MAPK14MAPK13MAPK12MAPK11NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |