Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692769 | 0.93 | KDM4E (0.49) | SOD1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL7695893 | 0.92 | SOD1 (0.46) | SOD1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL7700746 | 0.84 | JAK2 (0.48) | LMNAMAPK14MAPK12MAPK13MAPK11 | |
| SCHEMBL7694581 | 0.80 | SOD1 (0.74) | SOD1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL7691825 | 0.80 | JAK2 (0.46) | MAPTMAPK1NPSR1HPGDLMNA | |
| SCHEMBL7696799 | 0.77 | JAK2 (0.45) | MAPTLMNAHTTMAPK14MAPK12 | |
| SCHEMBL7697247 | 0.76 | MAPK14 (0.48) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL7692071 | 0.76 | MAPK14 (0.49) | GSK3AMAPK14MAPK12MAPK13MAPK11 | |
| SCHEMBL7693923 | 0.76 | MAPK14 (0.45) | MAPK14MAPK12MAPK13MAPK11JAK2 | |
| SCHEMBL7695414 | 0.75 | MAPK13 (0.42) | MAPTRAB9AMAPK1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |