Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321274 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7159306 | 0.81 | HPGD (0.52) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7860899 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7563366 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPC1HSD17B10KMT2AMEN1 | |
| SCHEMBL6318332 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6322737 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7158445 | 0.74 | UBE2N (0.35) | ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7156639 | 0.74 | RAB7A (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7159868 | 0.74 | HPGD (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7864344 | 0.73 | RAB7A (0.36) | ALDH1A1HPGDSMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410586-B1 | ANTICOAGULANTS; INSULIN RESISTANCE; ANTIALLERGENS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | disclosed |
| EP-1080068-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | Novo Nordisk A/S (DK) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999046237-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |