Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840164 | 0.85 | HDAC6 (0.50) | HDAC6ENPP2HDAC1HDAC2HDAC8 | |
| SCHEMBL4955033 | 0.84 | HDAC6 (0.69) | HDAC6ENPP2F2PLGELANE | |
| SCHEMBL7142639 | 0.83 | MEN1 (0.47) | HDAC6ENPP2ELANEMEN1KMT2A | |
| SCHEMBL839928 | 0.77 | LPL (0.41) | HDAC6ENPP2HDAC1HDAC2HDAC8 | |
| SCHEMBL6280723 | 0.77 | HDAC6 (0.61) | HDAC6ENPP2F2PLGELANE | |
| SCHEMBL7212064 | 0.76 | ENPP2 (0.53) | HDAC6ENPP2F2PLGELANE | |
| SCHEMBL1998644 | 0.76 | METAP2 (0.43) | HDAC6ENPP2PRMT5WDR77 | |
| SCHEMBL14582995 | 0.75 | PIK3CD (0.40) | HDAC6F2ELANECTSGCTRC | |
| SCHEMBL4872435 | 0.75 | KMT2A (0.52) | HDAC6ENPP2F2PLGELANE | |
| SCHEMBL13987067 | 0.74 | HDAC6 (0.52) | HDAC6ENPP2F2PLGELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |