Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249852 | 0.77 | GABRA1 (0.40) | PDE4APDE4CPDE4DALDH1A1MAPT | |
| SCHEMBL5116386 | 0.77 | LMNA (0.40) | LMNAALDH1A1TDP1MAPTTSHR | |
| SCHEMBL3294386 | 0.74 | TSHR (0.46) | LMNAALDH1A1TDP1MAPTTSHR | |
| SCHEMBL433554 | 0.72 | MEN1 (0.39) | LMNATDP1HTTSMN1; SMN2KMT2A | |
| SCHEMBL647834 | 0.72 | GABRA1 (0.34) | PDE4APDE4CPDE4DALDH1A1KDM4E | |
| SCHEMBL16289365 | 0.70 | LMNA (0.38) | LMNAALDH1A1TDP1MAPTTSHR | |
| SCHEMBL3144065 | 0.69 | LMNA (0.41) | LMNAALDH1A1TDP1MAPTTSHR | |
| SCHEMBL10818509 | 0.68 | GABRA1 (0.42) | LMNAALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL14124548 | 0.68 | KDM1A (0.37) | PDE4APDE4CPDE4DALDH1A1MAPT | |
| SCHEMBL5824067 | 0.68 | BACE1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002090328-A1 | THE PREPARATION OF SUBSTITUTED PYRIDINES UTILIZING NITRIC AND AN ANHYDRIDE | REILLY INDUSTRIES, INC. (US) | 2002-11-14 | — | — | WO | disclosed |