SCHEMBL249852

SCHEMBL249852

C=CCc1cccc(CC=C)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
KCNH2 Q12809 3/20 0.39
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
GRIN3A Q8TCU5 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CXCR4 P61073 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
XDH P47989 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124548 0.84 KDM1A (0.37) GABRA1GABRB2PDE4APDE4CPDE4D
SCHEMBL5824067 0.84 BACE1 (0.42) GABRA1GABRB2IMPDH2NOS1NOS2
SCHEMBL8522029 0.84 GABRA1 (0.34) GABRA1GABRB2NPSR1PDE4APDE4C
SCHEMBL10818509 0.84 GABRA1 (0.42) GABRA1GABRB2PGK1PGK2HRH4
SCHEMBL647834 0.84 GABRA1 (0.34) GABRA1GABRB2PGK1PGK2PDE4A
SCHEMBL17429701 0.84 CCR1 (0.43) GABRA1GABRB2NPSR1L3MBTL1ALDH1A1
SCHEMBL8515582 0.82 CYP4F2 (0.38) GABRB2PGK1PGK2NPSR1PDE4D
SCHEMBL6575962 0.80 P2RX7 (0.40) GABRA1ALDH1A1
SCHEMBL14270796 0.80 PDE10A (0.38) GABRA1GABRB2KCNH2ALDH1A1CYP3A4
SCHEMBL624018 0.80 KDM1A (0.41) ALDH1A1TP53CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192910-A1 POLYMERIZATION CATALYST COMPOSITION AND METHOD OF EMPLOYING SAME BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-06-22 US claimed
US-11584808-B2 Polymerization catalyst composition and method of employing same BRIDGESTONE CORPORATION (JP) 2023-02-21 US claimed
CN-110267965-B Method for producing ortho-metallated metal compounds 默克专利有限公司 2022-12-20 CN claimed
CN-109694454-B Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer 中国石油化工股份有限公司 2021-09-21 CN claimed
CN-109694453-B Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer 中国石油化工股份有限公司 2021-08-03 CN claimed
EP-3583111-B1 PROCESS FOR PREPARING ORTHO-METALLATED METAL COMPOUNDS MERCK PATENT GMBH (DE) 2020-12-23 EP claimed
US-20200048289-A1 PROCESS FOR PREPARING ORTHO-METALLATED METAL COMPOUNDS MERCK PATENT GMBH (DE) 2020-02-13 US claimed
US-8722956-B2 Kit for decomposing organophosphorus compounds QUEEN'S UNIVERSITY AT KINGSTON (US) 2014-05-13 US claimed
WO-2013033830-A1 METHOD FOR THE DETECTION OF CHEMICAL WARFARE AGENTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-03-14 WO claimed
EP-1613402-B1 METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS UNIV KINGSTON (CA) 2013-01-16 EP claimed
EP-1613402-A2 METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2006-01-11 EP claimed
US-20040230082-A1 Method of decomposing organophosphorus compounds QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-11-18 US claimed
EP-1041442-B1 Chemical amplification type positive resist SUMITOMO CHEMICAL CO (JP) 2004-10-27 EP claimed
WO-2004080543-A2 METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-09-23 WO claimed
US-6406830-B2 BIS(SULFONIUM METHYL)KETONE BISPERFLUOROALKANESULFONATE ACID GENERATOR WITH TRIPHENYLSULFONIUM OR DIPHENYLIODONIUM SALTS, AND A RESIN HAVING A UNIT UNSTABLE TO AN ACID, SUCH AS 2-ALKYL-2-ADAMANTYL (METH)ACRYLATE; RESOLUTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-18 US claimed
US-6348297-B1 COMPOSITION COMPRISING ACID GENERATOR COMPRISING ALIPHATIC SULFONIUM SALT, TRIPHENYLSULFONIUM OR DIPHENYLIODONIUM SALT,RESIN HAVING ACID-LABILE GROUP WHICH IS INSOLUBLE IN ALKALI BUT BECOMES SOLUBLE BY ACTION OF ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US claimed
US-20020006582-A1 Chemical amplification type positive resist compositions and sulfonium salts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-17 US claimed
EP-1154321-A1 Chemical amplification type positive resist compositions and sulfonium salts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP claimed
EP-1041442-A1 Chemical amplification type positive resist SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-04 EP claimed
US-5239081-A Preparation of photographic compounds EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048289-A1 PROCESS FOR PREPARING ORTHO-METALLATED METAL COMPOUNDS NISCH, SOD1, MDM4 GABRA1 3851/4885GABRB2 4197/4885KCNH2 1519/4885
US-20040230082-A1 Method of decomposing organophosphorus compounds ACHE, L3MBTL3, L3MBTL4 GABRA1 2689/4885GABRB2 2427/4885KCNH2 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.