SCHEMBL7697103

SCHEMBL7697103

C=CCc1cc2oc1cc2CC=C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.41
GABRA1 P14867 4/20 0.40
GABRB2 P47870 4/20 0.40
MAPT P10636 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
ALOX15 P16050 1/20 0.35
POLB P06746 3/20 0.34
ALDH1A1 P00352 2/20 0.33
PPARG P37231 2/20 0.33
PPARD Q03181 2/20 0.33
PPARA Q07869 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
MAPK1 P28482 1/20 0.33
XDH P47989 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
GAA P10253 2/20 0.32
CNR1 P21554 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4571041 0.75 ESR1 (0.38) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL10834079 0.75 SRD5A1 (0.39) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL44699 0.74 GABRA1 (0.48) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL9485968 0.70 GABRA1 (0.41) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL8967983 0.67 GABRA1 (0.44) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL4140872 0.67 ALOX5 (0.41) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL8970670 0.67 GABRA1 (0.38) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL7113611 0.67 GABRA1 (0.43) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL1744767 0.65 GABRA1 (0.58) SRD5A1GABRA1GABRB2MAPTCYP3A4
SCHEMBL6278626 0.65 GABRA1 (0.41) SRD5A1GABRA1GABRB2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002027587-A MEMBER FOR LOUDSPEAKER AND METHOD FOR MANUFACTURING THE SAME ONKYO CORP 2002-01-25 JP disclosed