Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744767 | 0.69 | GABRA1 (0.58) | GABRA1GABRB2SRD5A1POLBXDH | |
| SCHEMBL1420694 | 0.69 | GABRA1 (0.64) | GABRA1GABRB2SRD5A1POLBXDH | |
| SCHEMBL6309438 | 0.67 | GABRA1 (0.61) | GABRA1GABRB2SRD5A1POLBXDH | |
| SCHEMBL7697103 | 0.67 | SRD5A1 (0.41) | GABRA1GABRB2SRD5A1ESR1ESR2 | |
| SCHEMBL44699 | 0.67 | GABRA1 (0.48) | GABRA1GABRB2SRD5A1POLBXDH | |
| SCHEMBL2783485 | 0.67 | GABRA1 (0.45) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL4149652 | 0.65 | GABRA1 (0.59) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL5931901 | 0.65 | GABRA1 (0.48) | GABRA1GABRB2SRD5A1ESR1ESR2 | |
| SCHEMBL7737611 | 0.65 | GABRA1 (0.59) | GABRA1GABRB2SRD5A1POLBXDH | |
| SCHEMBL4045452 | 0.65 | GABRA1 (0.48) | GABRA1GABRB2ESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218084-A | POLYMERIZATION OF CARBON MONOXIDE/PROPYLENE WITH AROMATIC AMINE | SHELL OIL COMPANY (US) | 1993-06-08 | — | — | US | claimed |
| EP-0522635-B1 | Polymer preparation | SHELL INT RESEARCH (NL) | 1996-05-29 | — | — | EP | disclosed |
| EP-0490445-B1 | Catalyst compositions | SHELL INT RESEARCH (NL) | 1996-02-28 | — | — | EP | disclosed |
| US-5292700-A | Polymerization catalyst | SHELL OIL COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5292700-A | Polymerization catalyst | SHELL OIL COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5225523-A | POLYKETONE POLYMER PREPARATION WITH TETRA ALKYL BIS PHOSPHINE LIGAND AND HYDROGEN | SHELL OIL COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5218084-A | POLYMERIZATION OF CARBON MONOXIDE/PROPYLENE WITH AROMATIC AMINE | SHELL OIL COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| US-5218084-A | POLYMERIZATION OF CARBON MONOXIDE/PROPYLENE WITH AROMATIC AMINE | SHELL OIL COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0522635-A1 | Polymer preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-01-13 | — | — | EP | disclosed |
| EP-0490445-A2 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-17 | — | — | EP | disclosed |