Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7688425 | 0.88 | OGA (0.51) | OGAALDH1A1 | |
| SCHEMBL6131879 | 0.84 | OGA (0.59) | OGAMEN1KMT2AALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL6131897 | 0.83 | OGA (0.58) | OGAMEN1KMT2AALDH1A1ACHE | |
| SCHEMBL6131981 | 0.79 | OGA (0.61) | OGAPANK3 | |
| SCHEMBL6131831 | 0.78 | HTR1A (0.50) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7690290 | 0.77 | OGA (0.59) | OGAPANK3 | |
| Hydrochloric Acid SCHEMBL7690292 | 0.77 | OGA (0.59) | OGAPANK3 | |
| Hydrochloric Acid SCHEMBL7680845 | 0.74 | UTS2R (0.48) | ALDH1A1ACHE | |
| SCHEMBL6131851 | 0.73 | OGA (0.59) | OGAMEN1KMT2AALDH1A1ACHE | |
| Water SCHEMBL7685626 | 0.72 | OGA (0.58) | OGAMEN1KMT2AALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |