Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131908 | 0.89 | ALDH1A1 (0.58) | HTR1AHTR2ADRD2HTR7DRD3 | |
| Hydrochloric Acid SCHEMBL6132036 | 0.88 | ALDH1A1 (0.57) | HTR1AHTR2ADRD2HTR7DRD3 | |
| SCHEMBL6131881 | 0.84 | HTR1A (0.58) | HTR1AHTR2ADRD2HTR7DRD3 | |
| Hydrochloric Acid SCHEMBL6131899 | 0.83 | HTR1A (0.57) | HTR1AHTR2ADRD2HTR7DRD3 | |
| SCHEMBL6132095 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL6131982 | 0.78 | HTR1A (0.59) | HTR1AHTR2ADRD2HTR7DRD3 | |
| SCHEMBL7697105 | 0.78 | OGA (0.52) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6131783 | 0.77 | HTR1A (0.57) | HTR1AHTR2ADRD2HTR7DRD3 | |
| Hydrochloric Acid SCHEMBL6131948 | 0.75 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL6131854 | 0.74 | HTR1A (0.58) | HTR1AHTR2ADRD2HTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |