Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859041 | 0.94 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8863056 | 0.94 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL11261755 | 0.92 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL20758153 | 0.91 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL15535303 | 0.87 | CA1 (0.54) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10919387 | 0.86 | HSD11B1 (0.54) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL697819 | 0.86 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL15689511 | 0.86 | HTR6 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL20757768 | 0.85 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4537377 | 0.83 | NAMPT (0.50) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |