Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658590 | 0.94 | SIGMAR1 (0.50) | HTR2CSLC6A3SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL29114059 | 0.94 | SIGMAR1 (0.50) | HTR2CSLC6A3SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL31208355 | 0.93 | HTR2C (0.48) | HTR2CSLC6A3SIGMAR1TBXAS1TRPV1 | |
| SCHEMBL29654989 | 0.93 | HTR2C (0.48) | HTR2CSLC6A3SIGMAR1TBXAS1TRPV1 | |
| SCHEMBL830267 | 0.90 | SIGMAR1 (0.49) | HTR2CSLC6A3SIGMAR1 | |
| SCHEMBL28776115 | 0.90 | HTR2C (0.55) | HTR2CSLC6A3 | |
| SCHEMBL5623941 | 0.88 | HTR6 (0.51) | CYP19A1TBXAS1TRPV1PARP1PARP2 | |
| SCHEMBL4637304 | 0.85 | MTNR1A (0.53) | HTR2CSLC6A3 | |
| SCHEMBL2406501 | 0.83 | PARP1 (0.52) | SIGMAR1CYP19A1TBXAS1TRPV1PARP1 | |
| SCHEMBL10586712 | 0.83 | SIGMAR1 (0.53) | SIGMAR1CYP19A1TBXAS1TRPV1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017684-B1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1017684-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6083479-A | Contrast media for infarction and necrosis imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| WO-1999016757-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |