Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090790 | 0.98 | LMNA (0.58) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL17530460 | 0.95 | LMNA (0.50) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8080660 | 0.86 | MEN1 (0.57) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL7366543 | 0.86 | LMNA (0.69) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL17231059 | 0.85 | LMNA (0.60) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8081846 | 0.85 | LMNA (0.60) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8086789 | 0.85 | LMNA (0.60) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8081832 | 0.85 | LMNA (0.60) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL6246723 | 0.85 | THRB (0.49) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL9417688 | 0.85 | LMNA (0.60) | LMNACYP3A4MAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380181-B1 | AMINO ACID RESIDUES IN THE 3-AND/OR 4-POSITION FUNCTION AS SIDEROPHORES AND/OR AS BIOLOGICAL CHELATING AGENTS FOR IRON IN GRAM-NEGATIVE BACTERIA | GRUENENTHAL GMBH (DE) | 2002-04-30 | — | — | US | disclosed |