Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696957 | 0.84 | HTT (0.77) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL7696379 | 0.84 | HTT (0.77) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL7696910 | 0.77 | HTT (0.62) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL7694699 | 0.75 | HTT (0.59) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL8617215 | 0.75 | NPC1 (0.46) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL3720887 | 0.74 | HTT (0.47) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL7697608 | 0.73 | NPC1 (0.56) | ALDH1A1RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL2318897 | 0.73 | HTT (0.52) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL3916025 | 0.72 | HTT (0.72) | HTTALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL11083426 | 0.72 | ALDH1A1 (0.46) | HTTALDH1A1RAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |