⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787583 | 0.76 | — | — | |
| SCHEMBL28787237 | 0.71 | — | — | |
| SCHEMBL8733600 | 0.70 | — | — | |
| Biguanide SCHEMBL28879210 | 0.69 | — | — | |
| SCHEMBL8712304 | 0.69 | — | — | |
| Formaldehyde SCHEMBL11059062 | 0.69 | — | — | |
| SCHEMBL28481447 | 0.68 | — | — | |
| SCHEMBL3080488 | 0.67 | LMNA (0.33) | — | |
| Biguanide SCHEMBL4198353 | 0.67 | ACHE (0.40) | — | |
| SCHEMBL146394 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |