⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697745 | 0.76 | — | — | |
| Biguanide SCHEMBL17701180 | 0.69 | LDHA (0.35) | — | |
| Biguanide SCHEMBL4198353 | 0.69 | ACHE (0.40) | — | |
| SCHEMBL3080488 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL9809865 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL146394 | 0.69 | — | — | |
| Biguanide SCHEMBL18255803 | 0.67 | MAPK1 (0.31) | — | |
| Biguanide SCHEMBL8039 | 0.67 | — | — | |
| Biguanide SCHEMBL8973572 | 0.67 | ACHE (0.38) | — | |
| Bromide SCHEMBL10501190 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040553-B2 | Phenoxyisobutyric acid compounds and method of synthesis | Cell Viable Corporation (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2014-12-18 | — | — | US | disclosed |
| US-20140350045-A1 | PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS | LALEZARI IRAJ (US) | 2014-11-27 | — | — | US | disclosed |
| EP-2616430-A2 | NOVEL PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHODS FOR SYNTHESIS | Cell Viable Corporation (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20120232120-A1 | AMINO ACID AMIDES OF PHENOXYBUTYRIC ACID DERIVATIVES | LALEZARI IRAJ (US) | 2012-09-13 | — | — | US | disclosed |
| WO-2012050623-A2 | NOVEL PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHODS FOR SYNTHESIS | Cell Viable Corporation (US) | 2012-04-19 | — | — | WO | disclosed |
| US-20120071502-A1 | Novel phenoxyisobutyric acid compounds and methods for synthesis | Cell Viable Corporation (US) | 2012-03-22 | — | — | US | disclosed |
| US-8034966-B1 | Phenoxyisobutyric acid compounds and methods for synthesis | Cell Viable Corporation (US) | 2011-10-11 | — | — | US | disclosed |
| EP-1594492-B1 | NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGES) | HOPE CITY (US) | 2008-11-26 | — | — | EP | disclosed |
| EP-1370256-B1 | NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGES) | HOPE CITY (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7030133-B2 | Inhibitors of formation of advanced glycation endproducts (AGEs) | CITY OF HOPE (US) | 2006-04-18 | — | — | US | disclosed |
| US-20030220362-A1 | Novel inhibitors of formation of advanced glycation endproducts (AGEs) | CITY OF HOPE | 2003-11-27 | — | — | US | disclosed |
| US-6605642-B2 | Administering specified compounds which are derivatives of phenoxyisobutyric acids and of benzoic acid including aryl and heterocyclic ureido derivatives and aryl and heterocyclic carboxamido derivatives; treating aging, arthritis, diabetes | CITY OF HOPE | 2003-08-12 | — | — | US | disclosed |
| US-20020013256-A1 | Novel inhibitors of formation of advanced glycation endproducts (AGES) | PROSCIENCE CORPORATION, INCORPORATED IN THE STATE OF NEW YORK | 2002-01-31 | — | — | US | disclosed |
| US-4977189-A | Anxiolytic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4977189-A | Anxiolytic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4977189-A | Anxiolytic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1990-12-11 | — | — | US | disclosed |