Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691857 | 0.86 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1HPGDSLC2A1 | |
| SCHEMBL9828612 | 0.83 | F2 (0.56) | L3MBTL1KDM4EALDH1A1HPGDNQO2 | |
| SCHEMBL7699219 | 0.81 | ALDH1A1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDNQO2 | |
| SCHEMBL396614 | 0.77 | HPGD (0.64) | L3MBTL1KDM4EALDH1A1HPGDNQO2 | |
| SCHEMBL30065410 | 0.77 | HPGD (0.64) | L3MBTL1KDM4EALDH1A1HPGDNQO2 | |
| SCHEMBL7700056 | 0.76 | ALDH1A1 (0.55) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28611035 | 0.75 | HPGD (0.62) | L3MBTL1KDM4EALDH1A1HPGDNQO2 | |
| SCHEMBL3304514 | 0.75 | GAK (0.61) | KDM4ENQO2GAKFBP1ABCG2 | |
| SCHEMBL29892755 | 0.75 | GAK (0.61) | KDM4ENQO2GAKFBP1ABCG2 | |
| SCHEMBL27030369 | 0.75 | NQO2 (0.51) | KDM4EALDH1A1HPGDNQO2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |