Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619822 | 0.86 | CYP1A2 (0.51) | F2L3MBTL1DHFRLMNACYP1A2 | |
| SCHEMBL1224169 | 0.86 | L3MBTL1 (0.60) | F2L3MBTL1LMNACYP1A2KMT2A | |
| SCHEMBL7697958 | 0.83 | L3MBTL1 (0.49) | F2L3MBTL1LMNAKMT2ANQO2 | |
| SCHEMBL8936095 | 0.79 | POLB (0.64) | L3MBTL1DHFRLMNACYP1A2KMT2A | |
| SCHEMBL17657692 | 0.78 | POLB (0.61) | F2CYP1A2KMT2ANQO2MPO | |
| SCHEMBL9828211 | 0.77 | LMNA (0.47) | F2L3MBTL1DHFRLMNACYP1A2 | |
| SCHEMBL423891 | 0.77 | L3MBTL1 (0.71) | L3MBTL1LMNACYP1A2KMT2APOLB | |
| SCHEMBL25896032 | 0.75 | F2 (0.46) | F2L3MBTL1LMNAMPOACHE | |
| SCHEMBL6791268 | 0.75 | F2 (0.51) | F2KMT2ANQO2MPOACHE | |
| SCHEMBL17646468 | 0.75 | BACE1 (0.59) | F2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | disclosed |
| US-4587341-A | BACTERICIDES | BURROUGHS WELLCOME CO. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |