Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28900199 | 0.98 | KEAP1 (0.41) | KEAP1FFAR1CHRM1P4HTMCYP1A2 | |
| SCHEMBL12751702 | 0.89 | SMN1; SMN2 (0.46) | FFAR1CYP1A2HSD17B10ALDH1A1HDAC6 | |
| SCHEMBL28287788 | 0.87 | TBXAS1 (0.46) | HDAC6 | |
| SCHEMBL2561694 | 0.82 | CAPN1 (0.46) | FFAR1ALDH1A1 | |
| SCHEMBL30505617 | 0.82 | ALDH1A1 (0.42) | CYP1A2HSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL2633369 | 0.79 | ALDH1A1 (0.43) | HSD17B10ALDH1A1 | |
| SCHEMBL1321921 | 0.79 | — | — | |
| SCHEMBL21576133 | 0.78 | CYP1A2 (0.34) | CYP1A2HSD17B10ALDH1A1 | |
| Succinic Acid SCHEMBL29701135 | 0.78 | TSHR (0.35) | CHRM1 | |
| Hydrochloric Acid SCHEMBL25267909 | 0.78 | ALDH1A1 (0.37) | HSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480141-A | Pyranocoumarin derivative and preparation method and application thereof | 吉林大学珠海学院 | 2021-03-12 | — | — | CN | claimed |
| CN-110872254-A | Pyrazole salt diionic liquid and method for catalytic synthesis of cyclic carbonate by using same | 河南大学 | 2020-03-10 | — | — | CN | claimed |
| CN-105504305-B | One kind contains 3（4 pyridines）Coordination polymer of pyrazoles propionic acid and preparation method thereof, purposes | 郑州大学 | 2018-03-20 | — | — | CN | claimed |
| CN-105504305-A | Coordination polymer containing 3-(4-pyridine) pyrazole-propionic acid as well as preparation method and application thereof | UNIV ZHENGZHOU | 2016-04-20 | — | — | CN | claimed |
| CN-1085980-C | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 2002-06-05 | — | — | CN | claimed |
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-110872254-B | Pyrazole salt diionic liquid and method for catalytic synthesis of cyclic carbonate by using same | 河南大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-112480141-A | Pyranocoumarin derivative and preparation method and application thereof | 吉林大学珠海学院 | 2021-03-12 | — | — | CN | disclosed |
| CN-110872254-A | Pyrazole salt diionic liquid and method for catalytic synthesis of cyclic carbonate by using same | 河南大学 | 2020-03-10 | — | — | CN | disclosed |
| CN-109293551-A | Method and composition relevant to granulocyte colony stimulating factor receptor | 利亘制药公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-105504305-B | One kind contains 3（4 pyridines）Coordination polymer of pyrazoles propionic acid and preparation method thereof, purposes | 郑州大学 | 2018-03-20 | — | — | CN | disclosed |
| CN-105504305-A | Coordination polymer containing 3-(4-pyridine) pyrazole-propionic acid as well as preparation method and application thereof | UNIV ZHENGZHOU | 2016-04-20 | — | — | CN | disclosed |
| CN-105472986-A | Pyrazolyl pyrrolinones and their use as herbicides | SYNGENTA PARTICIPATIONS AG | 2016-04-06 | — | — | CN | disclosed |
| CN-105451557-A | Pyrazolyl pyrrolinones and their use as herbicides | SYNGENTA PARTICIPATIONS AG | 2016-03-30 | — | — | CN | disclosed |
| CN-104039761-A | Methods and compositions related to granulocyte colony stimulating factor receptor | LIGAND PHARM INC | 2014-09-10 | — | — | CN | disclosed |
| CN-1085980-C | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 2002-06-05 | — | — | CN | disclosed |
| WO-2002017912-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | disclosed |