Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528724 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL7000034 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL30563642 | 0.75 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL4742545 | 0.75 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL23705539 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL367474 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL29367804 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL11259902 | 0.74 | LMNA (0.76) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL23464966 | 0.74 | LMNA (0.76) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL338 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362170-B1 | Benzylglycosylamides as inhibitors of smooth muscle cell proliferation | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-26 | — | — | US | disclosed |
| US-6339064-B1 | FOR THERAPY OF RESTENOSIS | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-15 | — | — | US | disclosed |
| EP-1144426-A2 | BENZYLGLYCOSYLAMIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1133508-A2 | BENZYLGLYCOSYLAMIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031094-A2 | BENZYLGLYCOSYLAMIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |
| WO-2000031093-A2 | BENZYLGLYCOSYLAMIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |