Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695426 | 0.85 | GAA (0.49) | IKBKBMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7693990 | 0.81 | IKBKB (0.53) | IKBKBMAPTKMT2AMEN1RAB9A | |
| SCHEMBL7693745 | 0.81 | IKBKB (0.53) | IKBKBMAPTALDH1A1NR1H4NOTUM | |
| SCHEMBL7695239 | 0.79 | MAPT (0.55) | IKBKBMAPTKMT2AMEN1RAB9A | |
| SCHEMBL7699894 | 0.79 | IKBKB (0.54) | IKBKBMAPTKMT2AMEN1RAB9A | |
| SCHEMBL7991876 | 0.76 | NPBWR1 (0.59) | MAPTKMT2AMEN1L3MBTL1MMP2 | |
| SCHEMBL29158639 | 0.75 | GAA (0.48) | IKBKBMAPTKMT2AMEN1RAB9A | |
| SCHEMBL7694372 | 0.74 | TARBP2 (0.48) | IKBKBMAPTKMT2AMEN1RAB9A | |
| SCHEMBL7699591 | 0.74 | TARBP2 (0.62) | MAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL7695157 | 0.74 | IKBKB (0.48) | IKBKBMAPTKMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |