Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MGAM | O43451 | 3/20 | 0.55 |
| ▸ | SI | P14410 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700838 | 0.87 | RAB9A (0.55) | MAPTNPC1LMNARAB9AGAA | |
| SCHEMBL7699946 | 0.85 | AGER (0.55) | MAPTKDM4ERAB9AGAAPOLB | |
| SCHEMBL7699732 | 0.85 | RAB9A (0.53) | MAPTNPC1LMNARAB9AGAA | |
| SCHEMBL7989114 | 0.82 | MAPT (0.55) | MAPTNPC1LMNAKDM4ERAB9A | |
| SCHEMBL7697561 | 0.80 | POLB (0.54) | KDM4ERAB9AGAAPOLBALDH1A1 | |
| SCHEMBL7698064 | 0.79 | IKBKB (0.51) | MAPTNPC1LMNARAB9AALDH1A1 | |
| SCHEMBL7695426 | 0.74 | GAA (0.49) | MAPTNPC1KDM4ERAB9AGAA | |
| SCHEMBL3191246 | 0.73 | NPC1 (1.00) | MAPTNPC1LMNAKDM4ERAB9A | |
| SCHEMBL7978116 | 0.73 | LMNA (0.61) | MAPTNPC1LMNAKDM4ERAB9A | |
| SCHEMBL7977883 | 0.73 | LMNA (0.55) | MAPTNPC1LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |