Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257872 | 0.76 | NPC1 (0.36) | MAPK1HTR2CALDH1A1MEN1KMT2A | |
| SCHEMBL30108108 | 0.76 | NR3C2 (0.40) | HTR2CMEN1KMT2A | |
| SCHEMBL4709625 | 0.76 | MAPT (0.46) | MAPK1HTR2CALDH1A1MEN1KMT2A | |
| SCHEMBL5334814 | 0.76 | NPC1 (0.43) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL26507116 | 0.76 | NR3C2 (0.40) | HTR2CMEN1KMT2A | |
| SCHEMBL6257880 | 0.76 | NQO2 (0.34) | MAPK1HTR2CALDH1A1MEN1KMT2A | |
| SCHEMBL901629 | 0.76 | ACHE (0.57) | ACHEMAPK3MAPK1PTAFRALOX5 | |
| SCHEMBL7700239 | 0.75 | HTR2C (0.35) | HTR2CALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5331625 | 0.73 | ENPP2 (0.36) | RAB9A | |
| SCHEMBL31737879 | 0.73 | ENPP2 (0.36) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |