Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786361 | 0.76 | CYP19A1 (0.49) | ADRA1ACYP19A1HTR1AALDH1A1MAPT | |
| SCHEMBL7137746 | 0.76 | MEN1 (0.36) | MEN1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL7698079 | 0.75 | ACHE (0.40) | HTR2CMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL7094998 | 0.70 | ALDH1A1 (0.54) | HTR2AHTR2BADRA1AHTR1AMEN1 | |
| SCHEMBL7695325 | 0.70 | ALDH1A1 (0.54) | HTR2AHTR2BADRA1AHTR1AMEN1 | |
| SCHEMBL7487376 | 0.69 | CYP19A1 (0.33) | ADRA1ACYP19A1 | |
| SCHEMBL29474981 | 0.68 | HTR2C (0.50) | HTR2CHTR2AHTR2BADRA1ACYP19A1 | |
| SCHEMBL6484237 | 0.68 | HTR2C (0.50) | HTR2CHTR2AHTR2BADRA1ACYP19A1 | |
| SCHEMBL935859 | 0.68 | HTR2C (0.50) | HTR2CHTR2AHTR2BADRA1ACYP19A1 | |
| SCHEMBL7783854 | 0.67 | HPGD (0.36) | HTR2CHTR2AHTR2BADRA1ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |