Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596298 | 0.82 | PDE10A (0.57) | PDE10A | |
| Hydrochloric Acid SCHEMBL9989591 | 0.78 | PDE10A (0.52) | PDE10A | |
| SCHEMBL2593659 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596320 | 0.75 | PDE10A (0.50) | PDE10A | |
| SCHEMBL4083689 | 0.73 | ALDH1A1 (0.52) | PDE10A | |
| SCHEMBL7702929 | 0.69 | PDE10A (0.61) | PDE10A | |
| SCHEMBL27934468 | 0.68 | PDE10A (0.57) | PDE10A | |
| SCHEMBL7698016 | 0.67 | PDE10A (0.62) | PDE10A | |
| SCHEMBL16627993 | 0.66 | RIPK1 (0.47) | — | |
| SCHEMBL12049784 | 0.65 | OPRL1 (0.46) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |