Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158706 | 0.91 | TARBP2 (0.51) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7694080 | 0.88 | IKBKB (0.55) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29158624 | 0.87 | TARBP2 (0.65) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7694123 | 0.86 | KDM4E (0.53) | TARBP2IKBKBKDM4EALDH1A1KMT2A | |
| SCHEMBL7694372 | 0.84 | TARBP2 (0.48) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7693600 | 0.84 | TARBP2 (0.48) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7699428 | 0.82 | TARBP2 (0.53) | TARBP2IKBKBKDM4EALDH1A1KMT2A | |
| SCHEMBL29158621 | 0.81 | KMT2A (0.54) | TARBP2IKBKBKDM4EALDH1A1KMT2A | |
| SCHEMBL31466885 | 0.80 | TARBP2 (0.53) | TARBP2IKBKBKDM4EALDH1A1KMT2A | |
| SCHEMBL7701292 | 0.80 | TARBP2 (0.67) | TARBP2IKBKBSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |