Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189076 | 0.92 | TARBP2 (0.78) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4499055 | 0.92 | TARBP2 (0.73) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7696406 | 0.91 | TARBP2 (0.56) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7699490 | 0.88 | TARBP2 (0.67) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7694080 | 0.87 | IKBKB (0.55) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL16005699 | 0.87 | TARBP2 (0.72) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158677 | 0.87 | TARBP2 (0.72) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7701393 | 0.86 | TARBP2 (0.52) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7701068 | 0.86 | ALDH1A1 (0.69) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158615 | 0.86 | TARBP2 (0.65) | TARBP2ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |